A large-scale atlas of mouse brain cells has revealed that aging does not affect all brain cell types equally. Some cell populations show dramatic shifts in gene activity between youth and old age, ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Recent technological advances facilitate the reconstruction of complete brain connectomes in small organisms and partial ...

A chronological map of the fetal brain reveals when key cells emerge and provides clues about autism and cancer.

Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain, representing eight different brain regions and 36 different cell types to show clear epigenetic ...

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper published in Cell ...

A newly discovered mechanism that protects nerve cells could have important implications for understanding and treating mental illness.

A group of specialized cells play a crucial part in clearing toxic proteins from inside the brain 1. But in people with Alzheimer’s disease, these cells malfunction, leading to the build up of tau ...

Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody ...