Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Greenland sharks preserve vision for centuries through DNA repair, offering clues for treating age-related eye disease.

Greenland sharks use a unique DNA repair process to protect their eyesight, revealing clues about longevity and retinal preservation.

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

DNA-PK can help repair DNA double-stranded breaks in one of two ways. For breaks with missing information, it can target enzymes that can fill in missing nucleotides — sort of like a needle and thread ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Ultraviolet (UV) rays from sunlight can cause DNA damage that leads to skin aging and cancer. Fortunately, our bodies have a highly efficient repair system capable of swiftly identifying and repairing ...

Analyzing genomes from over 900,000 people, researchers found that short DNA repeats expand and destabilize with age. Common ...

A team of researchers has made a discovery that may have implications for therapeutic gene editing strategies, cancer diagnostics and therapies and other advancements in biotechnology. A team of ...