Human stem cells can differentiate into any human cell. But the process of dedifferentiation, essentially differentiation in reverse, is implicated in several diseases. Now researchers have uncovered ...

In the bone marrow, blood stem cells via precursor cells give rise to a variety of blood cell types with various functions: white blood cells, red blood cells, or blood platelets. In which cell type a ...

The process of cellular differentiation, in which human pluripotent stem cells (hPCSs) progress from primitive to developmentally advanced states, is a fundamental aspect of life. Understanding this ...

In the multicellular organism, cells develop from a single pluripotent/stem cell and differentiate into different cell types during proliferation. The gene regulatory network (GRN) plays an important ...