Embryonic stem cells (ESCs) exhibit unique chromatin features, including a permissive transcriptional program and an open, decondensed chromatin state. Induced pluripotent stem cells (iPSCs), which ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...

In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or ...

Cancer progression and relapse arise not only from genetic evolution but also from dynamic, reversible cell-state transitions that enable malignant cells to ...

All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is ...

Arthropod-borne viruses (arboviruses), such as dengue and Zika viruses, transmit widely across the globe, posing threats to ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as ...