MIT researchers have developed an experimental mRNA-based therapy that restored key immune functions lost with age in mice.

Researchers have used an experimental mRNA therapy to make old immune cells in mice behave as if they were young again, ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

The Kawasaki Innovation Center for NanoMedicine (iCONM; Director: Kazunori Kataoka; Location: Kawasaki, Japan) have announced with Tokyo Medical and Dental University, and Kyorin University that a ...

A trio of mRNA molecules could help guard against the harmful effects of aging on immune cells, a study in mice finds. A new ...

Stanford scientists have uncovered how mRNA COVID-19 vaccines can very rarely trigger heart inflammation in young men — and ...

Research on mRNA vaccines have been under fire in the post-pandemic age, but these immunotherapies are showing promise in the ...

LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...

Adding a photocopier gene to mRNA vaccines could make them last longer and curb side effects. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive ...