Salmonella bacteria (red) cause up to a million deaths a year worldwide and there is a need for effective vaccines. New work from UC Davis shows how salmonella-specific T-cells can be stimulated to ...

The complement system is a key component of innate and adaptive immunity and therefore acts as a vital defense against invading pathogens. Deficiencies in the complement system are associated with ...

The body defends itself against pathogens by depriving them of vital iron. However, this strategy doesn't always succeed against Salmonella. Researchers have discovered that these bacteria ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

C3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare and progressive kidney diseases that often lead to kidney failure. Both involve overactivity in ...

The body defends itself against pathogens by depriving them of vital iron. However, this strategy doesn't always succeed against Salmonella. Researchers at the University of Basel have discovered that ...