Human noroviruses are the leading cause of acute gastroenteritis worldwide, a major global health problem for which there are no specific treatments or vaccines. Understanding the first phase of ...

Understanding virus entry and the subsequent intracellular journey of individual virions is critical for elucidating mechanisms of infection and developing effective antiviral strategies. Recent ...

Semliki Forest virus was originally isolated from mosquitoes in the Semliki Forest, Uganda, hence the name. Upon systemic infection from mosquito bites, Semliki Forest virus causes mild blood viremia ...

Once the virus attaches to receptor clusters, it sends signals that make the cell wrap it in a clathrin coat and build an actin bulge, pulling the virus inward. The virus is then pinched off into a ...

One of the essential factors the COVID-19 virus needs to enter a host is a receptor on a human cell — a place where the universally recognized spike protein can latch onto the cell surface, pierce it, ...

In a recent study posted to the bioRxiv* preprint server, researchers proposed an optimal system to generate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-like particles (VLPs) ...

Scientists have captured a never-before-seen, high-resolution look at influenza’s stealthy invasion of human cells, revealing that the cells aren’t just helpless victims. Using a groundbreaking ...

The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for new broad-range antiviral medications. While many bacterial infections can be treated with the same medications, antiviral ...

For the first time, a new high-resolution microscopy technique has allowed researchers to watch live as influenza viruses infect cells. The international team led by ETH Zurich found that the cells ...

Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...

Varicella-zoster virus (VZV) causes chickenpox and shingles, while herpes simplex virus (HSV) is responsible for oral and genital herpes. Although current treatments mainly focus on inhibiting viral ...