Notably, the paper also includes simulation studies outlining when dDRTC is most effective, positioning it as a practical ...

Vividion publishes manuscript detailing the discovery and optimization of VVD-214, the company’s covalent inhibitor of WRN.

Pirtobrutinib (Jaypirca®), a first-in-class noncovalent Bruton tyrosine kinase (BTK) inhibitor, has been approved by the FDA for adults with relapsed or refractory chronic lymphocytic leukemia (CLL) ...

Scientists mapped where drugs bind inside the body, cell by cell, to better understand benefits and side effects.

Sequential BCL2 inhibitor therapy shows initial responses but lacks durability, especially in patients exposed to both BTKi ...

The discovery of a stable single-electron covalent bond between two carbon atoms validates a century-old theory. The discovery of a stable single-electron covalent bond between two carbon atoms ...

Prof. Hong Xu's team in Tsinghua University reports a substrate-assisted interfacial polymerization approach to easily prepare a uniform, large-area, and microcontinuous 3D-COF membrane, and ...

These results provide a design plan for battery materials. The use of Mg4C60 could lead to batteries that support fast ...

The covalent bond itself is a shared pair of electrons electrostatically attracted to the positive nuclei of two non-metal atoms. The atoms achieve a stable outer electron arrangement (a noble gas ...