IEEE Spectrum on MSN

Jimi Hendrix was a systems engineer

He precisely controlled modulation and feedback loops ...
RMD Open

Distinct pattern of comorbidities hinders treatment target attainment in SLE through persistent disease activity and delayed glucocorticoid tapering: longitudinal data fro…

Background Remission and low-disease activity are recommended targets in systemic lupus erythematosus (SLE), yet many ...
Open Heart

Artificial intelligence-based clustering to identify functional risk phenotypes in heart failure

Background Patients with heart failure (HF) frequently suffer from undetected declines in cardiorespiratory fitness (CRF), which significantly increases their risk of poor outcomes. However, current ...
Dot Physics on MSN

Building an elastic collision simulator with springs in Python

Building an elastic collision simulator with springs in Python to model realistic physics interactions and dynamic object collisions. Learn how to implement spring forces, momentum conservation, and ...
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...
eLife

Nuclear export governs TDP-43 phase transitions and cytoplasmic aggregation

This study presents valuable findings implicating nuclear export in the regulation of protein condensate behaviour and TDP-43 phase behaviour, suggesting a link to pathogenic aggregation in ALS/FTD.